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2 月 13 日(ri)(ri)(ri)，由濟(ji)民(min)(min)可(ke)(ke)(ke)信(xin)(xin)(xin)集(ji)團(tuan)(tuan)(tuan)(tuan)(tuan)(tuan)研(yan)(yan)(yan)(yan)(yan)(yan)(yan)(yan)(yan)究(jiu)(jiu)(jiu)(jiu)院(yuan)(yuan)開(kai)展(zhan)的(de)(de)(de)(de)(de)(de)(de) SARS-CoV-2 中(zhong)(zhong)和(he)抗(kang)(kang)體(ti)(ti)(ti)(ti)研(yan)(yan)(yan)(yan)(yan)(yan)(yan)(yan)(yan)發(fa)(fa)(fa)(fa)取(qu)得(de)(de)重(zhong)大(da)(da)進展(zhan)，研(yan)(yan)(yan)(yan)(yan)(yan)(yan)(yan)(yan)究(jiu)(jiu)(jiu)(jiu)人(ren)員(yuan)已(yi)獲得(de)(de)結合(he) SARS-CoV-2 S1 刺突糖(tang)蛋(dan)白且(qie)阻(zu)斷其與人(ren)受體(ti)(ti)(ti)(ti)蛋(dan)白結合(he)的(de)(de)(de)(de)(de)(de)(de)全(quan)(quan)人(ren)源(yuan)抗(kang)(kang)體(ti)(ti)(ti)(ti)。目(mu)(mu)前(qian)(qian)(qian)，該項(xiang)目(mu)(mu)已(yi)完成(cheng)南昌(chang)市第(di)一(yi)(yi)(yi)批新(xin)(xin)(xin)冠(guan)肺(fei)(fei)炎應急科研(yan)(yan)(yan)(yan)(yan)(yan)(yan)(yan)(yan)攻關(guan)(guan)(guan)項(xiang)目(mu)(mu)申報(bao)，并已(yi)獲得(de)(de)專項(xiang)資助(zhu)，相關(guan)(guan)(guan)研(yan)(yan)(yan)(yan)(yan)(yan)(yan)(yan)(yan)究(jiu)(jiu)(jiu)(jiu)正(zheng)進一(yi)(yi)(yi)步深入。 圖(tu)1 圖(tu)片(pian)引自：//thebiologynotes.com/2019-ncov-covid-19/ 自 2019 年(nian) 12 月 31 日(ri)(ri)(ri)在衛(wei)(wei)健(jian)委(wei)首次通報(bao)新(xin)(xin)(xin)冠(guan)肺(fei)(fei)炎病(bing)(bing)(bing)(bing)(bing)例后，新(xin)(xin)(xin)冠(guan)肺(fei)(fei)炎疫(yi)情(qing)在全(quan)(quan)國(guo)(guo)迅速蔓延，并向海外擴展(zhan)。由于(yu)新(xin)(xin)(xin)型冠(guan)狀病(bing)(bing)(bing)(bing)(bing)毒(du)（SARS-CoV-2，原用(yong)名 2019-nCoV，世界衛(wei)(wei)生組織于(yu) 2 月 11 日(ri)(ri)(ri)將新(xin)(xin)(xin)型冠(guan)狀病(bing)(bing)(bing)(bing)(bing)毒(du)感(gan)染(ran)(ran)的(de)(de)(de)(de)(de)(de)(de)肺(fei)(fei)炎命(ming)名為「COVID-19」，與此同時(shi)，國(guo)(guo)際病(bing)(bing)(bing)(bing)(bing)毒(du)分(fen)(fen)類(lei)委(wei)員(yuan)會聲明，將新(xin)(xin)(xin)型冠(guan)狀病(bing)(bing)(bing)(bing)(bing)毒(du)命(ming)名為「 SARS-CoV-2」）傳染(ran)(ran)性強、防(fang)(fang)控(kong)難度(du)大(da)(da)，疫(yi)情(qing)的(de)(de)(de)(de)(de)(de)(de)進展(zhan)引起了(le)黨和(he)國(guo)(guo)家的(de)(de)(de)(de)(de)(de)(de)高度(du)重(zhong)視，各(ge)(ge)地(di)迅速實施了(le)嚴格網格化(hua)(hua)隔(ge)離措(cuo)施，以控(kong)制(zhi)疫(yi)情(qing)的(de)(de)(de)(de)(de)(de)(de)進一(yi)(yi)(yi)步蔓延。雖然相關(guan)(guan)(guan)措(cuo)施當前(qian)(qian)(qian)已(yi)取(qu)得(de)(de)一(yi)(yi)(yi)定成(cheng)效(xiao)(xiao)，但由于(yu)目(mu)(mu)前(qian)(qian)(qian)尚無有(you)效(xiao)(xiao)疫(yi)苗或特(te)效(xiao)(xiao)藥(yao)(yao)物，疫(yi)情(qing)防(fang)(fang)治(zhi)(zhi)工作仍存在較大(da)(da)難度(du)，疫(yi)情(qing)發(fa)(fa)(fa)(fa)展(zhan)形勢嚴峻。 2 月 5 日(ri)(ri)(ri)，國(guo)(guo)家衛(wei)(wei)生健(jian)康(kang)委(wei)員(yuan)會在《新(xin)(xin)(xin)型冠(guan)狀病(bing)(bing)(bing)(bing)(bing)毒(du)感(gan)染(ran)(ran)的(de)(de)(de)(de)(de)(de)(de)肺(fei)(fei)炎診(zhen)療方案（試行第(di)五版）》中(zhong)(zhong)建議(yi)：使用(yong)康(kang)復病(bing)(bing)(bing)(bing)(bing)人(ren)的(de)(de)(de)(de)(de)(de)(de)血漿(jiang)輸入療法救治(zhi)(zhi)危(wei)重(zhong)病(bing)(bing)(bing)(bing)(bing)人(ren)。目(mu)(mu)前(qian)(qian)(qian)，已(yi)有(you)多(duo)個利用(yong)康(kang)復者特(te)異血漿(jiang)臨(lin)床治(zhi)(zhi)療危(wei)重(zhong)病(bing)(bing)(bing)(bing)(bing)人(ren)且(qie)效(xiao)(xiao)果顯著的(de)(de)(de)(de)(de)(de)(de)案例。畢竟血漿(jiang)制(zhi)品來源(yuan)有(you)限，且(qie)必(bi)須經(jing)過嚴格的(de)(de)(de)(de)(de)(de)(de)血液生物安全(quan)(quan)性檢測方能(neng)用(yong)于(yu)臨(lin)床，尚未(wei)充(chong)分(fen)(fen)滿足當前(qian)(qian)(qian)疫(yi)情(qing)防(fang)(fang)治(zhi)(zhi)的(de)(de)(de)(de)(de)(de)(de)需求。 1 月 24 日(ri)(ri)(ri)，濟(ji)民(min)(min)可(ke)(ke)(ke)信(xin)(xin)(xin)集(ji)團(tuan)(tuan)(tuan)(tuan)(tuan)(tuan)研(yan)(yan)(yan)(yan)(yan)(yan)(yan)(yan)(yan)究(jiu)(jiu)(jiu)(jiu)院(yuan)(yuan)大(da)(da)分(fen)(fen)子研(yan)(yan)(yan)(yan)(yan)(yan)(yan)(yan)(yan)發(fa)(fa)(fa)(fa)團(tuan)(tuan)(tuan)(tuan)(tuan)(tuan)隊多(duo)位(wei)專家經(jing)充(chong)分(fen)(fen)討論(lun)認為：利用(yong)基(ji)因工程(cheng)技術篩選(xuan)出具有(you)與康(kang)復者血漿(jiang)中(zhong)(zhong)抗(kang)(kang)體(ti)(ti)(ti)(ti)類(lei)似(si)功能(neng)的(de)(de)(de)(de)(de)(de)(de)中(zhong)(zhong)和(he)抗(kang)(kang)體(ti)(ti)(ti)(ti)，通過發(fa)(fa)(fa)(fa)酵(jiao)工程(cheng)實現(xian)(xian)大(da)(da)規模產業(ye)(ye)化(hua)(hua)應可(ke)(ke)(ke)滿足新(xin)(xin)(xin)冠(guan)肺(fei)(fei)炎疫(yi)情(qing)的(de)(de)(de)(de)(de)(de)(de)防(fang)(fang)治(zhi)(zhi)需求。當晚，在集(ji)團(tuan)(tuan)(tuan)(tuan)(tuan)(tuan)總部的(de)(de)(de)(de)(de)(de)(de)大(da)(da)力支(zhi)持下(xia)，新(xin)(xin)(xin)型冠(guan)狀病(bing)(bing)(bing)(bing)(bing)毒(du)中(zhong)(zhong)和(he)抗(kang)(kang)體(ti)(ti)(ti)(ti)的(de)(de)(de)(de)(de)(de)(de)研(yan)(yan)(yan)(yan)(yan)(yan)(yan)(yan)(yan)發(fa)(fa)(fa)(fa)項(xiang)目(mu)(mu)正(zheng)式啟動。 借助(zhu) 2019 年(nian)濟(ji)民(min)(min)可(ke)(ke)(ke)信(xin)(xin)(xin)集(ji)團(tuan)(tuan)(tuan)(tuan)(tuan)(tuan)自建的(de)(de)(de)(de)(de)(de)(de) 700 億級(ji)飛杰(jie)全(quan)(quan)人(ren)源(yuan)抗(kang)(kang)體(ti)(ti)(ti)(ti)文庫與自主(zhu)開(kai)發(fa)(fa)(fa)(fa)的(de)(de)(de)(de)(de)(de)(de)飛泰抗(kang)(kang)體(ti)(ti)(ti)(ti)發(fa)(fa)(fa)(fa)現(xian)(xian)平臺，研(yan)(yan)(yan)(yan)(yan)(yan)(yan)(yan)(yan)究(jiu)(jiu)(jiu)(jiu)人(ren)員(yuan)夜(ye)以繼(ji)日(ri)(ri)(ri)加班(ban)加點，克(ke)服因疫(yi)情(qing)導(dao)致(zhi)的(de)(de)(de)(de)(de)(de)(de)種種不便，于(yu) 2 月 13 日(ri)(ri)(ri)獲得(de)(de)了(le)結合(he) SARS-CoV-2 S1 刺突糖(tang)蛋(dan)白且(qie)阻(zu)斷其與人(ren)受體(ti)(ti)(ti)(ti)蛋(dan)白結合(he)的(de)(de)(de)(de)(de)(de)(de)全(quan)(quan)人(ren)源(yuan)抗(kang)(kang)體(ti)(ti)(ti)(ti)。 圖(tu)2 濟(ji)民(min)(min)可(ke)(ke)(ke)信(xin)(xin)(xin)集(ji)團(tuan)(tuan)(tuan)(tuan)(tuan)(tuan)研(yan)(yan)(yan)(yan)(yan)(yan)(yan)(yan)(yan)究(jiu)(jiu)(jiu)(jiu)院(yuan)(yuan)大(da)(da)分(fen)(fen)子研(yan)(yan)(yan)(yan)(yan)(yan)(yan)(yan)(yan)發(fa)(fa)(fa)(fa)團(tuan)(tuan)(tuan)(tuan)(tuan)(tuan)隊成(cheng)員(yuan) 目(mu)(mu)前(qian)(qian)(qian)，該項(xiang)目(mu)(mu)已(yi)獲得(de)(de)南昌(chang)市第(di)一(yi)(yi)(yi)批新(xin)(xin)(xin)冠(guan)肺(fei)(fei)炎應急科研(yan)(yan)(yan)(yan)(yan)(yan)(yan)(yan)(yan)攻關(guan)(guan)(guan)的(de)(de)(de)(de)(de)(de)(de)專項(xiang)資助(zhu)，相關(guan)(guan)(guan)研(yan)(yan)(yan)(yan)(yan)(yan)(yan)(yan)(yan)究(jiu)(jiu)(jiu)(jiu)正(zheng)在穩步推進；一(yi)(yi)(yi)旦(dan)證明抗(kang)(kang)體(ti)(ti)(ti)(ti)具有(you)中(zhong)(zhong)和(he)病(bing)(bing)(bing)(bing)(bing)毒(du)的(de)(de)(de)(de)(de)(de)(de)能(neng)力，有(you)望成(cheng)為新(xin)(xin)(xin)冠(guan)肺(fei)(fei)炎疫(yi)情(qing)防(fang)(fang)治(zhi)(zhi)的(de)(de)(de)(de)(de)(de)(de)特(te)效(xiao)(xiao)藥(yao)(yao)之(zhi)一(yi)(yi)(yi)。 據了(le)解，在新(xin)(xin)(xin)冠(guan)肺(fei)(fei)炎疫(yi)情(qing)發(fa)(fa)(fa)(fa)生后，濟(ji)民(min)(min)可(ke)(ke)(ke)信(xin)(xin)(xin)集(ji)團(tuan)(tuan)(tuan)(tuan)(tuan)(tuan)在立刻(ke)啟動相關(guan)(guan)(guan)藥(yao)(yao)物研(yan)(yan)(yan)(yan)(yan)(yan)(yan)(yan)(yan)發(fa)(fa)(fa)(fa)同時(shi)，還積極履行企(qi)業(ye)(ye)社會責任(ren)，在第(di)一(yi)(yi)(yi)時(shi)間向中(zhong)(zhong)國(guo)(guo)紅(hong)十字(zi)會總會捐(juan)款 100 萬元(yuan)用(yong)于(yu)武漢雷(lei)神山醫院(yuan)(yuan)建設(she)，并積極響應各(ge)(ge)地(di)需求捐(juan)贈抗(kang)(kang)疫(yi)藥(yao)(yao)物，截(jie)至目(mu)(mu)前(qian)(qian)(qian)各(ge)(ge)項(xiang)捐(juan)款及贈藥(yao)(yao)合(he)計金額已(yi)超過 1500 萬元(yuan)。 濟(ji)民(min)(min)可(ke)(ke)(ke)信(xin)(xin)(xin)集(ji)團(tuan)(tuan)(tuan)(tuan)(tuan)(tuan)是(shi)中(zhong)(zhong)國(guo)(guo)知(zhi)名的(de)(de)(de)(de)(de)(de)(de)現(xian)(xian)代(dai)化(hua)(hua)大(da)(da)健(jian)康(kang)產業(ye)(ye)集(ji)團(tuan)(tuan)(tuan)(tuan)(tuan)(tuan)，自 2016 年(nian)起連續(xu) 3 年(nian)蟬聯中(zhong)(zhong)國(guo)(guo)制(zhi)藥(yao)(yao)工業(ye)(ye)百強前(qian)(qian)(qian)十；2018 年(nian) 5 月，濟(ji)民(min)(min)可(ke)(ke)(ke)信(xin)(xin)(xin)集(ji)團(tuan)(tuan)(tuan)(tuan)(tuan)(tuan)研(yan)(yan)(yan)(yan)(yan)(yan)(yan)(yan)(yan)究(jiu)(jiu)(jiu)(jiu)院(yuan)(yuan)落(luo)戶(hu)上(shang)海張江科學城，進入全(quan)(quan)球前(qian)(qian)(qian)沿醫藥(yao)(yao)研(yan)(yan)(yan)(yan)(yan)(yan)(yan)(yan)(yan)究(jiu)(jiu)(jiu)(jiu)領域；2019 年(nian)，濟(ji)民(min)(min)可(ke)(ke)(ke)信(xin)(xin)(xin)集(ji)團(tuan)(tuan)(tuan)(tuan)(tuan)(tuan)入選(xuan)新(xin)(xin)(xin)華社民(min)(min)族品牌工程(cheng)。